Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.5
USERS' SCORE
Good
Based on 11 Reviews
8
Supplement Facts
Serving Size: 1 Nugget
Amount Per Serving
%DV
Vitamin B12 (as methylcobalamin)
1000 mcg
41,667%
Top Medical Research Studies
9
We focused on whether white button mushrooms could help lower cholesterol levels and blood sugar in rats. In our study, we found that after three weeks of the mushroom powder, diabetic rats showed significant drops in glucose and triglyceride levels.
Furthermore, in hypercholesterolemic rats, a four-week treatment led to impressive reductions in total cholesterol and LDL cholesterol. Overall, these findings suggest that white button mushrooms may have beneficial effects on cholesterol and blood sugar management, at least in rat models.
Furthermore, in hypercholesterolemic rats, a four-week treatment led to impressive reductions in total cholesterol and LDL cholesterol. Overall, these findings suggest that white button mushrooms may have beneficial effects on cholesterol and blood sugar management, at least in rat models.
Read More
7
We examined the effects of Secholex, an anion-exchange gel, on high cholesterol in 46 patients with severe hyperlipoproteinemia over various studies. The results revealed that Secholex effectively lowered cholesterol levels, achieving a 15% reduction after the first year and 13% during the second year. While it was less effective than cholestyramine in increasing bile acid excretion, many patients preferred Secholex. However, it’s important to note that a third of patients experienced limited reductions in cholesterol, indicating varying responses.
Read More
9
We explored the effects of partial ileal bypass (PIB) on cholesterol levels in a small group of young adults with hyperlipidemia. After the surgical procedure, participants received vitamin B12 injections twice monthly.
Impressively, total plasma cholesterol levels decreased significantly three months after surgery and remained lower after one year. However, while PIB helped normalize cholesterol, it didn't completely prevent the progression of atherosclerosis in some patients. This indicates that while B12 treatment benefited cholesterol levels, it wasn't a cure-all for other cardiovascular issues we studied.
Impressively, total plasma cholesterol levels decreased significantly three months after surgery and remained lower after one year. However, while PIB helped normalize cholesterol, it didn't completely prevent the progression of atherosclerosis in some patients. This indicates that while B12 treatment benefited cholesterol levels, it wasn't a cure-all for other cardiovascular issues we studied.
Read More
Most Useful Reviews
9
Boosts overall well-being
1 people found this helpful
I suffer from pernicious anaemia. After using a sublingual B12 spray, I still felt terrible, but I switched to this brand without cyanide and had excellent results. I feel amazing now and highly recommend this product. I wish they offered Methylcobalamin and Adenosylcobalamin, which I am now trying.
Read More
7.5
Decreased homocysteine levels
1 people found this helpful
After taking this for six months due to B12 deficiency and high homocysteine levels (8), my homocysteine fell to 5 and my iron levels increased. I take it occasionally in sublingual form, which is very convenient.
Read More
7.5
Cholesterol reduction
1 people found this helpful
Solgar is my favourite brand, and I chose these vitamins. The tablets are small and easily digestible. Methylcobalamin is the active form of vitamin B12, which is well absorbed in our bodies and helps reduce cholesterol. I was pleased with the product and recommend it for prophylaxis.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.5
- All Researches
9
We explored how a specific dietary supplement that includes Vitamin B12 affects cholesterol levels in individuals with moderate high cholesterol. In our study, 80 participants were split into a treatment group and a control group.
After 6 months, the group taking the supplement experienced a notable drop in total cholesterol (TC) and improvements in other cholesterol types, while the control group showed no significant changes outside of TC reduction.
This suggests that, while a healthy diet and exercise can help, the addition of such supplements, including Vitamin B12, may enhance cholesterol management more effectively.
After 6 months, the group taking the supplement experienced a notable drop in total cholesterol (TC) and improvements in other cholesterol types, while the control group showed no significant changes outside of TC reduction.
This suggests that, while a healthy diet and exercise can help, the addition of such supplements, including Vitamin B12, may enhance cholesterol management more effectively.
Read More
9
We focused on whether white button mushrooms could help lower cholesterol levels and blood sugar in rats. In our study, we found that after three weeks of the mushroom powder, diabetic rats showed significant drops in glucose and triglyceride levels.
Furthermore, in hypercholesterolemic rats, a four-week treatment led to impressive reductions in total cholesterol and LDL cholesterol. Overall, these findings suggest that white button mushrooms may have beneficial effects on cholesterol and blood sugar management, at least in rat models.
Furthermore, in hypercholesterolemic rats, a four-week treatment led to impressive reductions in total cholesterol and LDL cholesterol. Overall, these findings suggest that white button mushrooms may have beneficial effects on cholesterol and blood sugar management, at least in rat models.
Read More
9
We explored the effects of partial ileal bypass (PIB) on cholesterol levels in a small group of young adults with hyperlipidemia. After the surgical procedure, participants received vitamin B12 injections twice monthly.
Impressively, total plasma cholesterol levels decreased significantly three months after surgery and remained lower after one year. However, while PIB helped normalize cholesterol, it didn't completely prevent the progression of atherosclerosis in some patients. This indicates that while B12 treatment benefited cholesterol levels, it wasn't a cure-all for other cardiovascular issues we studied.
Impressively, total plasma cholesterol levels decreased significantly three months after surgery and remained lower after one year. However, while PIB helped normalize cholesterol, it didn't completely prevent the progression of atherosclerosis in some patients. This indicates that while B12 treatment benefited cholesterol levels, it wasn't a cure-all for other cardiovascular issues we studied.
Read More
8
We explored the effects of vitamins B12, B6, and folic acid on cholesterol and homocysteine levels in 24 male patients with high triglycerides and cholesterol issues. Over 120 days, patients took specific doses of these vitamins while researchers measured their lipid and homocysteine levels at various intervals.
While we saw a notable decrease in homocysteine levels and triglycerides, high-density lipoprotein (HDL) did increase slightly. However, overall cholesterol levels did not significantly change.
This suggests that while vitamin B supplementation can affect certain lipids and lower homocysteine, it may not drastically alter cholesterol levels in these patients.
While we saw a notable decrease in homocysteine levels and triglycerides, high-density lipoprotein (HDL) did increase slightly. However, overall cholesterol levels did not significantly change.
This suggests that while vitamin B supplementation can affect certain lipids and lower homocysteine, it may not drastically alter cholesterol levels in these patients.
Read More
8
We explored how adding plant sterols to orange juice can impact cholesterol levels in mildly hypercholesterolemic individuals. In this study, 72 healthy participants enjoyed either regular orange juice or a fortified version for eight weeks.
Those drinking the fortified juice saw a decrease in total cholesterol by 7.2%, LDL cholesterol by 12.4%, and non-HDL cholesterol by 7.8%. However, we found no changes in HDL cholesterol or triglyceride levels. The results suggest that plant sterol-fortified orange juice can be a simple addition to a cholesterol-lowering diet.
Those drinking the fortified juice saw a decrease in total cholesterol by 7.2%, LDL cholesterol by 12.4%, and non-HDL cholesterol by 7.8%. However, we found no changes in HDL cholesterol or triglyceride levels. The results suggest that plant sterol-fortified orange juice can be a simple addition to a cholesterol-lowering diet.
Read More
User Reviews
USERS' SCORE
Good
Based on 11 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Boosts overall well-being
1 people found this helpful
I suffer from pernicious anaemia. After using a sublingual B12 spray, I still felt terrible, but I switched to this brand without cyanide and had excellent results. I feel amazing now and highly recommend this product. I wish they offered Methylcobalamin and Adenosylcobalamin, which I am now trying.
Read More
7.5
Decreased homocysteine levels
1 people found this helpful
After taking this for six months due to B12 deficiency and high homocysteine levels (8), my homocysteine fell to 5 and my iron levels increased. I take it occasionally in sublingual form, which is very convenient.
Read More
7.5
Cholesterol reduction
1 people found this helpful
Solgar is my favourite brand, and I chose these vitamins. The tablets are small and easily digestible. Methylcobalamin is the active form of vitamin B12, which is well absorbed in our bodies and helps reduce cholesterol. I was pleased with the product and recommend it for prophylaxis.
Read More
9
Effective assistance
Simply the best B12! This high-quality vitamin B12 is in its active form and absorbs instantly in the body. I administered this to my mother during Covid to combat convulsions, which increased sharply during her illness. It performed excellently! There were no side effects noted when she took it. We now keep it constantly in the first-aid kit for our parents, and at the first sign of a relapse, we utilise it immediately. It’s certainly an effective product! Wishing all health and happiness! If you liked my review, please give it a like.
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7.5
Highly effective absorption
116 people found this helpful
B 12 in this form is the best. It is absorbed much more effectively than the typical type, resulting in higher efficacy.
Read More
Frequently Asked Questions
7.5
Decreased homocysteine levels
1 people found this helpful
After taking this for six months due to B12 deficiency and high homocysteine levels (8), my homocysteine fell to 5 and my iron levels increased. I take it occasionally in sublingual form, which is very convenient.
7.5
Enhanced overall well-being
1 people found this helpful
Solgar Sublingual Methylcobalamin (Vitamin B12) 1000 mcg is an excellent way to provide the body with the necessary vitamin B12. The sublingual form ensures quick and effective absorption without needing to swallow a tablet. I’ve noticed an improvement in my energy and overall well-being after using this product. Solgar maintains high quality standards, and this vitamin B12 exemplifies their reliability.
2
No improvement noted
No noticeable changes. This vitamin was recommended by my attending physician due to repeated thrombosis in my right limb. The aim was to monitor homocysteine levels before and after two months of taking it. Unfortunately, the results were unsatisfactory, as the level even increased by one unit. Perhaps this is simply a response from my body rather than an issue with the vitamin itself.
9
Boosts overall well-being
1 people found this helpful
I suffer from pernicious anaemia. After using a sublingual B12 spray, I still felt terrible, but I switched to this brand without cyanide and had excellent results. I feel amazing now and highly recommend this product. I wish they offered Methylcobalamin and Adenosylcobalamin, which I am now trying.
9
Numbness relief
8 people found this helpful
This product proved to be highly useful. I experienced numbness in one of my toes, and thankfully it disappeared after just three uses. I wholeheartedly recommend it.
7.5
Cholesterol reduction
1 people found this helpful
Solgar is my favourite brand, and I chose these vitamins. The tablets are small and easily digestible. Methylcobalamin is the active form of vitamin B12, which is well absorbed in our bodies and helps reduce cholesterol. I was pleased with the product and recommend it for prophylaxis.
7.5
Highly effective absorption
116 people found this helpful
B 12 in this form is the best. It is absorbed much more effectively than the typical type, resulting in higher efficacy.
7
We examined a multi-ingredient supplement (MIS) featuring red yeast rice and omega-3 fatty acids to see how it impacts cholesterol levels in patients without cardiovascular disease.
In our pilot study involving 19 participants, we found that the MIS significantly reduced total cholesterol and LDL cholesterol levels. While those on the combined regimen of MIS and omega-3 saw a drop in triglycerides, the change wasn't significant, likely due to the small participant group.
Overall, the MIS shows promise in helping with cholesterol management and may improve patient compliance.
In our pilot study involving 19 participants, we found that the MIS significantly reduced total cholesterol and LDL cholesterol levels. While those on the combined regimen of MIS and omega-3 saw a drop in triglycerides, the change wasn't significant, likely due to the small participant group.
Overall, the MIS shows promise in helping with cholesterol management and may improve patient compliance.
9
We explored how a specific dietary supplement that includes Vitamin B12 affects cholesterol levels in individuals with moderate high cholesterol. In our study, 80 participants were split into a treatment group and a control group.
After 6 months, the group taking the supplement experienced a notable drop in total cholesterol (TC) and improvements in other cholesterol types, while the control group showed no significant changes outside of TC reduction.
This suggests that, while a healthy diet and exercise can help, the addition of such supplements, including Vitamin B12, may enhance cholesterol management more effectively.
After 6 months, the group taking the supplement experienced a notable drop in total cholesterol (TC) and improvements in other cholesterol types, while the control group showed no significant changes outside of TC reduction.
This suggests that, while a healthy diet and exercise can help, the addition of such supplements, including Vitamin B12, may enhance cholesterol management more effectively.
7
B12 treatment shows no significant cholesterol benefit
We explored the effects of a daily combination of plant sterols, fish oil, and B vitamins on cholesterol levels in hypercholesterolemic young individuals over 16 weeks.
While we observed significant reductions in total cholesterol and LDL cholesterol, the impact of B12 treatment specifically did not lead to marked improvements in high cholesterol.
Interestingly, triacylglycerol levels decreased slightly but were not statistically significant. Overall, this evidence suggests that while the combination may help manage cholesterol, B12 does not create a standout difference on its own.
While we observed significant reductions in total cholesterol and LDL cholesterol, the impact of B12 treatment specifically did not lead to marked improvements in high cholesterol.
Interestingly, triacylglycerol levels decreased slightly but were not statistically significant. Overall, this evidence suggests that while the combination may help manage cholesterol, B12 does not create a standout difference on its own.
8
We explored the effects of vitamins B12, B6, and folic acid on cholesterol and homocysteine levels in 24 male patients with high triglycerides and cholesterol issues. Over 120 days, patients took specific doses of these vitamins while researchers measured their lipid and homocysteine levels at various intervals.
While we saw a notable decrease in homocysteine levels and triglycerides, high-density lipoprotein (HDL) did increase slightly. However, overall cholesterol levels did not significantly change.
This suggests that while vitamin B supplementation can affect certain lipids and lower homocysteine, it may not drastically alter cholesterol levels in these patients.
While we saw a notable decrease in homocysteine levels and triglycerides, high-density lipoprotein (HDL) did increase slightly. However, overall cholesterol levels did not significantly change.
This suggests that while vitamin B supplementation can affect certain lipids and lower homocysteine, it may not drastically alter cholesterol levels in these patients.
References
- Wright N, Wilson L, Smith M, Duncan B, McHugh P. The BROAD study: A randomised controlled trial using a whole food plant-based diet in the community for obesity, ischaemic heart disease or diabetes. Nutr Diabetes. 2017;7:e256. doi:10.1038/nutd.2017.3
- Hobbs T, Caso R, McMahon D, Nymark M. A novel, multi-ingredient supplement to manage elevated blood lipids in patients with no evidence of cardiovascular disease: a pilot study. Altern Ther Health Med. 2014;20:18.
- Lombardo F, Lunghi R, Pallotti F, Palumbo A, Senofonte G, et al. Effects of a dietary supplement on cholesterol in subjects with moderate hypercholesterolemia. Clin Ter. 2013;164:e147. doi:10.7417/CT.2013.1556
- Garaiova I, Muchová J, Nagyová Z, Mišľanová C, Oravec S, et al. Effect of a plant sterol, fish oil and B vitamin combination on cardiovascular risk factors in hypercholesterolemic children and adolescents: a pilot study. Nutr J. 2013;12:7. doi:10.1186/1475-2891-12-7
- Jeong SC, Jeong YT, Yang BK, Islam R, Koyyalamudi SR, et al. White button mushroom (Agaricus bisporus) lowers blood glucose and cholesterol levels in diabetic and hypercholesterolemic rats. Nutr Res. 2010;30:49. doi:10.1016/j.nutres.2009.12.003
- Morón de Salim AR, Garcés Pasamontes A. [Effect of the supplementation of vitamins B12, B6 and folic acid on homocysteine and plasmatic lipids in patients with hyperlipoproteinemic secondary type IV]. Arch Latinoam Nutr. 2005;55:28.
- Devaraj S, Jialal I, Vega-López S. Plant sterol-fortified orange juice effectively lowers cholesterol levels in mildly hypercholesterolemic healthy individuals. Arterioscler Thromb Vasc Biol. 2004;24:e25.
- MacMahon M, Kirkpatrick C, Cummings CE, Clayton A, Robinson PJ, et al. A pilot study with simvastatin and folic acid/vitamin B12 in preparation for the Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine (SEARCH). Nutr Metab Cardiovasc Dis. 2000;10:195.
- Defraigne JO, Pirenne J, Swinnen JC, Honore P, Jacquet N, et al. [Value and limits of bypassing the distal ileum in the treatment of hypercholesterolemia]. J Chir (Paris). 1990;127:76.
- Nikkila EA, Miettinen TA, Lanner A. Treatment of hypercholesterolemia with Secholex. A long-term clinical trial and comparison with cholestyramine. Atherosclerosis. 1976;24:407.
